By integrating the key European teams in genomics, bioinformatics, animal health and animal models, EADGENE has enabled:
- The gathering of a critical mass of scientists and a unique access of complementary resources across host and pathogen models.
- The development of innovative functional genomics so that it has become a powerful tool in veterinary molecular medicine and has contributed to a better understanding of host-pathogen interactions, for the improvement of animal health and food safety.

Building from these benefits, EADGENE_S will ensure a long-term integration of the European resources in animal disease genomics grouping together the leading institutions. It will strengthen durably the creation of a core group of European research centres of excellence highly committed to integrating their resources and national facilities. To achieve this, EADGENE_S will:
(1) Expend, share and upgrade common research tools and platforms for joint research projects.
(2) Further develop common research methods, standards and protocols.
(3) Maintain, consolidate and further develop high quality common research projects on animal genomics and genetics in Europe.
(4) Support strategies for durable integration, particularly by providing opportunities for further funding.
(5) Consolidate the skills and expertise throughout the partnership with a programme of workshops, training courses, short-term missions, internships and studentships.
(6) Provide platforms for the development, management and dissemination of knowledge.
(7) Ensure efficient technology transfer to the industry to ensure timely commercialisation newest developments.

This integration will be fulfilled under the framework of the European Research Group EADGENE (EADGENE ERG), a co-operation instrument composed of the EADGENE members as represented by their respective participating research departments.

- To identify genes, gene products and pathways involved in host-pathogen interactions with the highest potential impact for improving animal health and decresing risks to humans.

- To identify standards and procedures for the monitoring and control of pathogens, and the risks caused by such pathogens.

- To identify and evaluate genomics tools and strategies for the control of pathogens affecting animal health and risks to humans.

1) Studying the genome - environment interactions and the resulting physiological processes that underlie health traits and that are significantly modulated by environmental factors, in particular pathogens (Salmonella, E. coli, Campylobacter and a group of pathogens that cause bovine/ovine mastitis).

2) The identification of molecular variation (genes, DNA markers) and molecular "signatures" (transcriptomic, proteomic, metabolic profiles) associated with disease susceptibility traits using high throughput genomics technologies.

3) The development of tools and strategies to modulate biological processes underlying health traits by using the knowledge generated within 1) and 2).

The European Animal Disease Genomics Group for Animal Health and FoodSafety (EADGENE ERG) coordinates a genomics approach to the unravelling of host-pathogen interactions, thereby providing the basic knowledge necessary for the development of new or improved therapeutics and vaccines, improved diagnostics, and the breeding of farm animals for disease resistance. This research will impact upon human health and lifestyle choices by concentrating on pathogens of importance in the food chain and will help ensure that Europe retains its status as a world leader in animal health for years to come.

Genómica y Mejora Animal

Code PAIDI: AGR-231

Juan José Garrido Pavón. partner. 

Universidad de Córdoba

Budget of Andalusian group: € 72,300.00

• Universidad de Córdoba